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Plácido Navas Selected Research

coenzyme Q10 (CoQ10)

9/2021Cellular Models for Primary CoQ Deficiency Pathogenesis Study.
7/2021Secondary CoQ10 deficiency, bioenergetics unbalance in disease and aging.
1/2020Design of High-Throughput Screening of Natural Extracts to Identify Molecules Bypassing Primary Coenzyme Q Deficiency in Saccharomyces cerevisiae.
1/2018Coenzyme Q10 Supplementation in Aging and Disease.
3/2017Biochemical Assessment of Coenzyme Q10 Deficiency.
1/2017Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency.
3/2016Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content.
1/2016Coenzyme Q10 and Pyridoxal Phosphate Deficiency Is a Common Feature in Mucopolysaccharidosis Type III.
1/2016RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7.
11/2015Determination of urinary coenzyme Q10 by HPLC with electrochemical detection: Reference values for a paediatric population.
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Plácido Navas Research Topics

Disease

18Mitochondrial Diseases (Mitochondrial Disease)
11/2021 - 03/2009
15Coenzyme Q10 Deficiency
11/2021 - 07/2006
7Inflammation (Inflammations)
12/2020 - 08/2007
6Neoplasms (Cancer)
06/2011 - 04/2006
2Rare Diseases (Rare Disease)
07/2021 - 01/2020
2Cardiovascular Diseases (Cardiovascular Disease)
01/2018 - 04/2014
2Ataxia (Dyssynergia)
11/2014 - 03/2013
2MELAS Syndrome (Syndrome, MELAS)
11/2012 - 08/2011
2Paralysis (Palsy)
06/2012 - 01/2005
2Necrosis
07/2007 - 03/2003
2Cerebellar Ataxia (Dysmetria)
01/2007 - 07/2006
2Myeloid Leukemia (Leukemia, Myelocytic)
06/2005 - 01/2005
1Metabolic Diseases (Metabolic Disease)
11/2021
1COVID-19
12/2020
1Pneumonia (Pneumonitis)
12/2020
1Hypoxia (Hypoxemia)
10/2020
1Weight Gain
05/2020
1Inborn Genetic Diseases (Disease, Hereditary)
01/2020
1Liver Diseases (Liver Disease)
09/2019
1Mitochondrial Myopathies (Mitochondrial Myopathy)
09/2019
1Muscular Diseases (Myopathy)
09/2019
1Cognitive Dysfunction
03/2019
1Memory Disorders (Memory Loss)
03/2019
1Nervous System Diseases (Neurological Disorders)
10/2018
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2018
1Chronic Disease (Chronic Diseases)
01/2018
1Kidney Diseases (Kidney Disease)
01/2018
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018
1Brain Diseases (Brain Disorder)
03/2016
1Mucopolysaccharidoses
01/2016
1Disease Progression
12/2015
1Malnutrition (Nutritional Deficiencies)
10/2015
1Myoclonic Epilepsies (Myoclonic Encephalopathy)
11/2014
1Dysarthria (Spastic Dysarthria)
11/2014
1Renal Insufficiency (Renal Failure)
03/2013
1Amyloid Plaque
06/2012
1Alzheimer Disease (Alzheimer's Disease)
06/2012
1Lung Neoplasms (Lung Cancer)
11/2010

Drug/Important Bio-Agent (IBA)

19coenzyme Q10 (CoQ10)IBA
09/2021 - 01/2005
12UbiquinoneIBA
11/2021 - 01/2005
9AntioxidantsIBA
01/2018 - 04/2006
4EnzymesIBA
01/2016 - 03/2003
4Reactive Oxygen Species (Oxygen Radicals)IBA
10/2015 - 03/2003
4Mitochondrial DNA (mtDNA)IBA
11/2012 - 01/2009
3Superoxides (Superoxide)IBA
10/2020 - 01/2005
3Fatty Acids (Saturated Fatty Acids)IBA
09/2019 - 10/2015
3Oxidoreductases (Dehydrogenase)IBA
08/2016 - 06/2007
3Amitriptyline (Elavil)FDA LinkGeneric
07/2011 - 03/2009
3CamptothecinIBA
11/2010 - 04/2006
3Proteins (Proteins, Gene)FDA Link
09/2009 - 03/2003
2CholesterolIBA
05/2020 - 10/2018
2LipidsIBA
09/2019 - 11/2014
2Mitochondrial Proteins (Mitochondrial Protein)IBA
09/2019 - 03/2009
2Amyloid (Amyloid Fibrils)IBA
03/2019 - 06/2012
2Messenger RNA (mRNA)IBA
01/2016 - 03/2003
2Transfer RNA (tRNA)IBA
11/2012 - 08/2011
2Pharmaceutical PreparationsIBA
11/2012 - 11/2010
2Olive OilIBA
04/2012 - 11/2006
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2011 - 06/2007
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2011 - 03/2003
2Methotrexate (Mexate)FDA LinkGeneric
11/2010 - 04/2006
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2010 - 04/2006
2SecurinIBA
02/2009 - 03/2008
2WortmanninIBA
01/2009 - 11/2008
2Dicumarol (Dicoumarol)FDA Link
03/2008 - 06/2005
1Explosive Agents (Explosives)IBA
12/2020
1CytokinesIBA
12/2020
1Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
10/2020
1Triglycerides (Triacylglycerol)IBA
05/2020
1Phosphotransferases (Kinase)IBA
09/2019
1Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2019
1SynaptophysinIBA
03/2019
1Electron-Transferring Flavoproteins (Electron Transfer Flavoprotein)IBA
08/2016
1SteroidsIBA
05/2016
1Hormones (Hormone)IBA
05/2016
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
05/2016
1Fish OilsIBA
05/2016
1Pyruvic Acid (Pyruvate)IBA
03/2016
1Pyridoxal Phosphate (Pyridoxal 5 Phosphate)IBA
01/2016
1ubiquinone 7IBA
01/2016
1GlycosaminoglycansIBA
01/2016
1Phospholipids (Phosphatides)FDA LinkGeneric
10/2015
1ResveratrolIBA
04/2015
1Glucose (Dextrose)FDA LinkGeneric
11/2014
1Lipoproteins (Lipoprotein)IBA
07/2014
1Adenosine Triphosphate (ATP)IBA
07/2014
1CarbonIBA
07/2014
1Riboflavin (Vitamin B2)FDA LinkGeneric
11/2012
1Leu Transfer RNAIBA
11/2012
1Peptides (Polypeptides)IBA
06/2012
1Sunflower OilIBA
04/2012
1Cyclosporine (Ciclosporin)FDA LinkGeneric
08/2011
1InterleukinsIBA
06/2011
1InterferonsIBA
06/2011
1Interleukin-10 (Interleukin 10)IBA
06/2011
1Immunoglobulin A (IgA)IBA
06/2011
1Oxidants (Oxidizing Agents)IBA
11/2010

Therapy/Procedure

3Therapeutics
12/2020 - 01/2007
1Caloric Restriction
04/2015
1Ketogenic Diet
11/2014